Learning

Organometallic Reagents in Carbon–Carbon Bond Formation

Nucleophilic Addition to Carbonyls → Chemoselectivity and Protecting Groups

This advanced learning path guides students specializing in organic synthesis through the fundamental principles and applications of organometallic reagents for forming carbon–carbon bonds. It covers Grignard reagents, organolithium compounds, organocuprates, and palladium-catalyzed cross-coupling reactions, integrating retrosynthetic analysis to apply these tools in complex synthesis planning.