Learning

Generation and Use of Transgenic Mice

Mouse as a Model Organism → Behavioral and Metabolic Phenotyping

This advanced learning path guides graduate-level developmental biologists through the principles and techniques for generating and using transgenic mice. It covers foundational mouse biology, the two major transgenic strategies (pronuclear injection and ES cell targeting), conditional gene targeting with Cre-lox, and the essential phenotyping approaches required to analyze mutant models.