Learning

Long-Read Structural Variant Detection

Basic NGS Fundamentals → SV Validation and Interpretation

This advanced learning path guides genomics researchers through the process of detecting large structural variants using long-read sequencing data. It covers the necessary foundations in sequencing technologies and alignment, progresses through specialized SV calling algorithms and assembly-based approaches, and includes practical validation strategies. The path emphasizes the unique advantages of PacBio and Oxford Nanopore data for resolving complex genomic rearrangements.